Tuesday, December 30, 2014
Harvoni Treatment...Over the Hump
Happy Holidays! I am one happy girl here! I only have 3 weeks of treatment left for Hepatitis C, Type 1, and I have just gotten a job doing research. I will be starting my new job on February 15th of 2015 without this nasty virus in me and thanks to the Harvoni treatment that I have been taking for the past 9 weeks! I don't think I could of accepted this job with the virus as active as it was before I started treatment. I am grateful and look forward to 2015!
As the treatment goes on I find that the side effects have gotten worse, but are still not terrible like the old treatment regimen. I definitely have a bad case of insomnia and I get diarrhea almost all the time. The holiday goodies, that have been everywhere, may be a big cause of this though. I also get really frustrated at times and am pretty painful in my joints. I have found that if I take a half of Tramadol when the pain is bad I can deal with it. I also try to think of the end result...being virus free! Yippie! I am anxious as can be and I only have 3 more weeks until that time is here! I know that there is a 4% chance that the virus will not go away, but I have a lot of faith that it is gone forever and all thanks to the new antiviral drug Harvoni!
I hope that your new year is great and if you have Hep C, Type 1, start treatment with this new antiviral drug...it works great!
Thursday, December 4, 2014
Harvoni - One Month into Treatment
Picture courtesy of RX List:
It's been 5 weeks since I started the new treatment for Hepatitis C, type 1, with the drug Harvoni and I am now virus free! Amazing as it may seem, I am. My recent blood results showed no detection of the virus! Now...I still have to take Harvoni for another 7 weeks, but there really are no terrible side effects like the ones you get with the old treatment regimen (Interferon, Ribavirin, & Incivek), low platelets, low red & white blood counts, and little to no energy. I have not actually looked at my blood tests, but the doctor said all was in normal range. Seven more weeks is not so bad, I am almost over the hump already! The old treatment lasted nine months and my treatment had to be terminated because my white blood got really low and my doctor lowered my dosage of Interferon ...the virus came back at that time. This new treatment is much better!
In the first month of treatment with Harvoni I have experienced some side effects, but they aren't so bad. My body has been pretty painful and I have trouble sleeping through the night. I also get pretty irrittable at times, when I am tired, hungry, or stressed. Knowing this, I try to be very conscious of my state of mind, exercise, and eat well. This works pretty well for the side effects of Harvoni...the new wonder drug of the cure of Hepatitis C, type 1!
Looks like 2015 is going to be a great year for me...yippie!
Hope it is for you too! I'll check back soon!
It's been 5 weeks since I started the new treatment for Hepatitis C, type 1, with the drug Harvoni and I am now virus free! Amazing as it may seem, I am. My recent blood results showed no detection of the virus! Now...I still have to take Harvoni for another 7 weeks, but there really are no terrible side effects like the ones you get with the old treatment regimen (Interferon, Ribavirin, & Incivek), low platelets, low red & white blood counts, and little to no energy. I have not actually looked at my blood tests, but the doctor said all was in normal range. Seven more weeks is not so bad, I am almost over the hump already! The old treatment lasted nine months and my treatment had to be terminated because my white blood got really low and my doctor lowered my dosage of Interferon ...the virus came back at that time. This new treatment is much better!
In the first month of treatment with Harvoni I have experienced some side effects, but they aren't so bad. My body has been pretty painful and I have trouble sleeping through the night. I also get pretty irrittable at times, when I am tired, hungry, or stressed. Knowing this, I try to be very conscious of my state of mind, exercise, and eat well. This works pretty well for the side effects of Harvoni...the new wonder drug of the cure of Hepatitis C, type 1!
Looks like 2015 is going to be a great year for me...yippie!
Hope it is for you too! I'll check back soon!
Monday, November 10, 2014
Harvoni Treatment - Two Weeks In
It has been a little over two weeks since I started taking Harvoni for the treatment of Hep C and I feel pretty good! I do have a little bit of all of the side effects (Fatigue, Headache, Nausea, Diarrhea, & Insomnia), but they only occur if I overdo anything. For instance if I eat a lot of processed food, I get diarrhea and nausea and if I sleep or rest to much during the day I get insomnia. Headaches come with to much stress! So my advice to anyone taking this treatment is to eat well, (little to no processed food with high fructose corn syrup or high glycemic indexes), exercise, drink plenty of water (64oz per day), and try really hard to eliminate stress from your life.
Easier said than done though...I know! Just having this nasty virus is stressful and the thought of the treatment not working and the consequences of it not working are even more stressful! The treatment time is relatively short and just having a little faith does wonders though! I try to not obsess on what used to be and think about how wonderful my life is going to be. I eat well and exercise every day. I also mark each day off on a calendar which reminds me that I have gotten that much farther into becoming virus free!
Til' the next time...be good and have faith!
Monday, November 3, 2014
Harvoni & Me - Treatment
Hi there! On Wednesday, October 29th, I started the new antiviral drug for treatment of Hepatitis C, type 1, Harvoni, and I have to say I have little to no side effects from the drug! I take the pill...yes...1 pill, 1 time per day, with my Nexium (for acid reflux) together, with water, on a fasted stomach, first thing in the morning, and then go about my day. I already have more energy and really look forward to becoming virus free!
I was amazed when my doctor said I didn't need to come back to get blood tests for another month and then again when my 12 weeks of treatment were done. She said the virus should be undetected in a month and should not reappear again! Hooray!!!
This is definitely history being made! For those of you that don't know my history with Hep C you can read about it in one of my previous posts or to give you a brief summary; I went through 9 months of treatment with Interferon, Ribavirin, & Incivek (3 months). I was virus free in 3 months and 1 week and continued treatment for another 6 months because my detection levels were not undetectable at 3 months. I had a very adverse reaction to Incivek, a bad rash, but continued the drug for 3 months as prescribed. At 9 months my white blood count went to dangerous levels and my doctor lowered my Interferon dose to help bring it back up. At this point the nasty virus came back and my treatment was discontinued. Needless to say, I was devastated! It took 6 months to get the drugs out of my system before I could start another treatment. I hoped and prayed that, in that time, a new and improved drug would come out because it was pretty obvious that the treatment I tried was not working for me.
It was a year before I was ready to try treatment again and during this time the virus had taken over my system and I was going down fast. I knew it was imperative that I start treatment soon or I was going to die from the Hep C virus. I was and am very nervous about the effectiveness of this medicine due to my past experience, but I have to say I now feel great about it and am very hopeful about my future because of this new Hepatitis C, type 1, antiviral drug, Harvoni! I really look forward to the upcoming holidays!
Sunday, October 19, 2014
History is being made - Ledipasvir & Sofobuvir - Harvoni
History is being made with the new FDA Approved Hepatitus C - Genotype 1 treatment: Ledipasir-Sofosbuvir, otherwise known as Harvoni. The new antiviral drug is a single pill, once daily dose that has up to a 99% cure rate!
Duration of treatment varies due to the amount of liver damage and past treatment experience.
Treatment naïve with or without cirrhosis 12 weeks
Treatment experienced** without cirrhosis 12 weeks
Treatment experienced** with cirrhosis 24 weeks
*Consider treatment duration of 8weeks in treatment-naïve patients without cirrhosis who have a pretreatment HCV RNA less than 6 million IU/mL
**Treatment-experienced patients who have failed treatment with either (a) peginterferon alfa plus ribavirin or (b) HCV protease inhibitor plus peginterferon alfa plus ribavirin
Source: Harvoni Prescribing Information. Gilead Sciences
There are some side effects, but none of them appear to be serious: Fatigue, Headache, Nausea, Diarrhea, & Insomnia.
Source: Harvoni Prescribing Information. Gilead Sciences
You can read the full article here: Ledipasvir-Sofobuvir (Harvoni)
This is a major breakthrough for the many people that are infected with Hepatitus C - Genotype 1, which happens to be the hardest hepatitus to cure.
Cures rates are as follows:
Among the 440 patients who underwent randomization and were treated, 20% had cirrhosis and 79% had HCV genotype 1a infection. The rates of sustained virology response were high, 94% in all treatment groups:
12 weeks of ledipasvir–sofosbuvir = 96%
12 weeks of ledipasvir–sofosbuvir and ribavirin = 99%
24 weeks of ledipasvir–sofosbuvir = 99%
24 weeks of ledipasvir–sofosbuvir and ribavirin = 99%
Ledipasvir and Sofosbuvir for Previously Treated HCV Genotype 1 Infection
I hope and pray that this is the antiviral medication that will cure my Hepatitus C, type 1a. I will be starting treatment in a couple of weeks!
Tuesday, July 22, 2014
The Fight to Help Us Become Virus Free...The Drug Companies!
This is a very promising article about a new Hep C treatment plan in the pill form...
Japan Approves First All-Oral, Interferon- and Ribavirin-Free Hepatitis C Treatment, Daklinza® (daclatasvir) and Sunvepra® (asunaprevir) Dual Regimen
Offers new treatment option for genotype 1 HCV patients in Japan who are interferon-ineligible/intolerant, or did not previously respond to treatment
Japanese HCV patients in urgent need of care now have opportunity for cure, including older patients and those with compensated cirrhosis
Monday, July 7, 2014 7:00 am EDT
"This milestone underscores the company’s commitment to delivering innovative medicines to patients with the highest unmet needs, and we believe Daklinza-based regimens will play a significant role in the evolution of HCV treatment for patients in Japan, and globally."
PRINCETON, N.J.--(BUSINESS WIRE)--Bristol-Myers Squibb Company (NYSE:BMY) announced today that the Japanese Ministry of Health, Labor and Welfare (MHLW) has approved Daklinza® (daclatasvir), a potent, pan-genotypic NS5A replication complex inhibitor (in vitro), and Sunvepra® (asunaprevir), a NS3/4A protease inhibitor, providing a new treatment that can lead to cure for many patients in Japan who currently have no treatment options. The Daklinza+Sunvepra Dual Regimen is Japan’s first all-oral, interferon- and ribavirin-free treatment regimen for patients with genotype 1 chronic hepatitis C virus (HCV) infection, including those with compensated cirrhosis.
“Japan has a unique hepatitis C patient population, many of whom are older and have been unable to take, or respond to, traditional therapies, so we have a real sense of urgency to treat these patients now,” said a lead study investigator Kazuaki Chayama of Hiroshima University in Japan. “The approval of the Daklinza+Sunvepra Dual Regimen offers for the first time a treatment option that addresses many of the unmet needs for our HCV patients.”
Of the 1.2 million people living with HCV in Japan, approximately 70% have genotype 1b. Further, a significant number of patients with HCV in Japan are over the age of 65, leading to more disease-related complications and a decreased likelihood of tolerating interferon-based therapies, the historical standard of care for treating HCV.
“The approval of Daklinza+Sunvepra in Japan reflects our strategic focus on developing a treatment option that meets the needs of the Japanese HCV patient population,” said Lamberto Andreotti, chief executive officer, Bristol-Myers Squibb. “This milestone underscores the company’s commitment to delivering innovative medicines to patients with the highest unmet needs, and we believe Daklinza-based regimens will play a significant role in the evolution of HCV treatment for patients in Japan, and globally.”
The Daklinza+Sunvepra Dual Regimen
The indications for Daklinza and Sunvepra in Japan are for the improvement of viraemia in either of the following patients with chronic hepatitis C genotype 1, or chronic hepatitis C genotype 1 with compensated cirrhosis: (1) patients who are ineligible or intolerant to interferon-based therapy, and (2) patients who have failed to respond to interferon-based therapy.
The approval is supported by results from a Phase III study demonstrating that the 24-week regimen of Daklinza and Sunvepra achieved overall SVR24 (sustained virologic response 24 weeks after the end of treatment; a functional cure) among 84.7% of Japanese HCV patients with genotype 1b. Among patients 65 years of age or older who were either interferon-ineligible or intolerant, 91.9% achieved SVR24. Further, patients with compensated cirrhosis present at baseline had overall SVR24 rates of 90.9%.
The regimen used in the Phase III study resulted in low rates of discontinuation (5%) due to adverse events (AEs). In addition, the rate of serious adverse events (SAEs) was low (5.9%) and few SAEs were experienced by more than one patient. Nasopharyngitis was the most common AE in the study (30.2%).
Results from the HALLMARK-Dual study, the Phase III multinational clinical trial investigating the Daklinza+Sunvepra Dual Regimen among genotype 1b HCV patients, demonstrated similar results to the Japan registration study and support filings in countries that have a high prevalence of genotype 1b, such as Korea and Taiwan.
About Bristol-Myers Squibb’s HCV Portfolio
Bristol-Myers Squibb’s research efforts are focused on advancing late-stage compounds to deliver the most value to patients with hepatitis C. At the core of our pipeline is daclatasvir, a potent pan-genotypic NS5A complex inhibitor (in vitro), which continues to be investigated in multiple treatment regimens and in people with co-morbidities, and is undergoing regulatory review in the U.S. and Europe.
Daclatasvir is being studied in combination with sofosbuvir in high unmet need patients, such as pre- and post-transplant patients, HIV/HCV co-infected patients, and patients with genotype 3, as part of the ongoing Phase III ALLY Program.
In 2014, the U.S. Food and Drug Administration (FDA) granted Bristol-Myers Squibb’s investigational Daclatasvir+Asunaprevir Dual Regimen Breakthrough Therapy Designation for use as a combination therapy in the treatment of genotype 1b HCV infection.
In 2013, Bristol-Myers Squibb’s investigational all-oral 3DAA Regimen (daclatasvir/asunaprevir/BMS-791325) also received Breakthrough Therapy Designation in the U.S., which helped to expedite the start of the ongoing Phase III UNITY Program. Study populations include non-cirrhotic naïve, cirrhotic naïve and previously treated patients. The daclatasvir 3DAA regimen is being studied as a fixed-dose-combination treatment with twice daily dosing.
About Hepatitis C
Globally, there are 150 million people infected with HCV, with genotype 1 being the most prevalent. Hepatitis C is a virus that infects the liver and is transmitted through direct contact with infected blood and blood products. Up to 90 percent of those infected with hepatitis C will not spontaneously clear the virus and will become chronically infected. According to the World Health Organization, 20 percent of people with chronic hepatitis C will develop cirrhosis and, of those, about 5 to 7 percent of patients may ultimately die of the consequences of infection.
About Bristol-Myers Squibb
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. For more information, please visit http://www.bms.com or follow us on Twitter at http://twitter.com/bmsnews.
Bristol-Myers Squibb Forward Looking Statement
This press release contains "forward-looking statements" as that term is defined in the Private Securities Litigation Reform Act of 1995 regarding the research, development and commercialization of pharmaceutical products. Such forward-looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual outcomes and results to differ materially from current expectations. No forward-looking statement can be guaranteed. Among other risks, there can be no guarantee that daclatasvir or asunaprevir or any other compounds mentioned in this release will receive regulatory approval in other countries or that they will become commercially successful products. Forward-looking statements in this press release should be evaluated together with the many uncertainties that affect Bristol-Myers Squibb's business, particularly those identified in the cautionary factors discussion in Bristol-Myers Squibb's Annual Report on Form 10-K for the year ended December 31, 2013, in our Quarterly Reports on Form 10-Q and our Current Reports on Form 8-K. Bristol-Myers Squibb undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.
Contact:
Bristol-Myers Squibb
Media:
Carrie Fernandez, 609-252-4831
cell: 215-859-2605
carrie.fernandez@bms.com
or
Investors:
Ranya Dajani, 609-252-5330
ranya.dajani@bms.com
or
Ryan Asay, 609-252-5020
ryan.asay@bms.com
All we have to do is hang in there until this treatment is approved in the United States...October maybe! Hang!!
Japan Approves First All-Oral, Interferon- and Ribavirin-Free Hepatitis C Treatment, Daklinza® (daclatasvir) and Sunvepra® (asunaprevir) Dual Regimen
Offers new treatment option for genotype 1 HCV patients in Japan who are interferon-ineligible/intolerant, or did not previously respond to treatment
Japanese HCV patients in urgent need of care now have opportunity for cure, including older patients and those with compensated cirrhosis
Monday, July 7, 2014 7:00 am EDT
"This milestone underscores the company’s commitment to delivering innovative medicines to patients with the highest unmet needs, and we believe Daklinza-based regimens will play a significant role in the evolution of HCV treatment for patients in Japan, and globally."
PRINCETON, N.J.--(BUSINESS WIRE)--Bristol-Myers Squibb Company (NYSE:BMY) announced today that the Japanese Ministry of Health, Labor and Welfare (MHLW) has approved Daklinza® (daclatasvir), a potent, pan-genotypic NS5A replication complex inhibitor (in vitro), and Sunvepra® (asunaprevir), a NS3/4A protease inhibitor, providing a new treatment that can lead to cure for many patients in Japan who currently have no treatment options. The Daklinza+Sunvepra Dual Regimen is Japan’s first all-oral, interferon- and ribavirin-free treatment regimen for patients with genotype 1 chronic hepatitis C virus (HCV) infection, including those with compensated cirrhosis.
“Japan has a unique hepatitis C patient population, many of whom are older and have been unable to take, or respond to, traditional therapies, so we have a real sense of urgency to treat these patients now,” said a lead study investigator Kazuaki Chayama of Hiroshima University in Japan. “The approval of the Daklinza+Sunvepra Dual Regimen offers for the first time a treatment option that addresses many of the unmet needs for our HCV patients.”
Of the 1.2 million people living with HCV in Japan, approximately 70% have genotype 1b. Further, a significant number of patients with HCV in Japan are over the age of 65, leading to more disease-related complications and a decreased likelihood of tolerating interferon-based therapies, the historical standard of care for treating HCV.
“The approval of Daklinza+Sunvepra in Japan reflects our strategic focus on developing a treatment option that meets the needs of the Japanese HCV patient population,” said Lamberto Andreotti, chief executive officer, Bristol-Myers Squibb. “This milestone underscores the company’s commitment to delivering innovative medicines to patients with the highest unmet needs, and we believe Daklinza-based regimens will play a significant role in the evolution of HCV treatment for patients in Japan, and globally.”
The Daklinza+Sunvepra Dual Regimen
The indications for Daklinza and Sunvepra in Japan are for the improvement of viraemia in either of the following patients with chronic hepatitis C genotype 1, or chronic hepatitis C genotype 1 with compensated cirrhosis: (1) patients who are ineligible or intolerant to interferon-based therapy, and (2) patients who have failed to respond to interferon-based therapy.
The approval is supported by results from a Phase III study demonstrating that the 24-week regimen of Daklinza and Sunvepra achieved overall SVR24 (sustained virologic response 24 weeks after the end of treatment; a functional cure) among 84.7% of Japanese HCV patients with genotype 1b. Among patients 65 years of age or older who were either interferon-ineligible or intolerant, 91.9% achieved SVR24. Further, patients with compensated cirrhosis present at baseline had overall SVR24 rates of 90.9%.
The regimen used in the Phase III study resulted in low rates of discontinuation (5%) due to adverse events (AEs). In addition, the rate of serious adverse events (SAEs) was low (5.9%) and few SAEs were experienced by more than one patient. Nasopharyngitis was the most common AE in the study (30.2%).
Results from the HALLMARK-Dual study, the Phase III multinational clinical trial investigating the Daklinza+Sunvepra Dual Regimen among genotype 1b HCV patients, demonstrated similar results to the Japan registration study and support filings in countries that have a high prevalence of genotype 1b, such as Korea and Taiwan.
About Bristol-Myers Squibb’s HCV Portfolio
Bristol-Myers Squibb’s research efforts are focused on advancing late-stage compounds to deliver the most value to patients with hepatitis C. At the core of our pipeline is daclatasvir, a potent pan-genotypic NS5A complex inhibitor (in vitro), which continues to be investigated in multiple treatment regimens and in people with co-morbidities, and is undergoing regulatory review in the U.S. and Europe.
Daclatasvir is being studied in combination with sofosbuvir in high unmet need patients, such as pre- and post-transplant patients, HIV/HCV co-infected patients, and patients with genotype 3, as part of the ongoing Phase III ALLY Program.
In 2014, the U.S. Food and Drug Administration (FDA) granted Bristol-Myers Squibb’s investigational Daclatasvir+Asunaprevir Dual Regimen Breakthrough Therapy Designation for use as a combination therapy in the treatment of genotype 1b HCV infection.
In 2013, Bristol-Myers Squibb’s investigational all-oral 3DAA Regimen (daclatasvir/asunaprevir/BMS-791325) also received Breakthrough Therapy Designation in the U.S., which helped to expedite the start of the ongoing Phase III UNITY Program. Study populations include non-cirrhotic naïve, cirrhotic naïve and previously treated patients. The daclatasvir 3DAA regimen is being studied as a fixed-dose-combination treatment with twice daily dosing.
About Hepatitis C
Globally, there are 150 million people infected with HCV, with genotype 1 being the most prevalent. Hepatitis C is a virus that infects the liver and is transmitted through direct contact with infected blood and blood products. Up to 90 percent of those infected with hepatitis C will not spontaneously clear the virus and will become chronically infected. According to the World Health Organization, 20 percent of people with chronic hepatitis C will develop cirrhosis and, of those, about 5 to 7 percent of patients may ultimately die of the consequences of infection.
About Bristol-Myers Squibb
Bristol-Myers Squibb is a global biopharmaceutical company whose mission is to discover, develop and deliver innovative medicines that help patients prevail over serious diseases. For more information, please visit http://www.bms.com or follow us on Twitter at http://twitter.com/bmsnews.
Bristol-Myers Squibb Forward Looking Statement
This press release contains "forward-looking statements" as that term is defined in the Private Securities Litigation Reform Act of 1995 regarding the research, development and commercialization of pharmaceutical products. Such forward-looking statements are based on current expectations and involve inherent risks and uncertainties, including factors that could delay, divert or change any of them, and could cause actual outcomes and results to differ materially from current expectations. No forward-looking statement can be guaranteed. Among other risks, there can be no guarantee that daclatasvir or asunaprevir or any other compounds mentioned in this release will receive regulatory approval in other countries or that they will become commercially successful products. Forward-looking statements in this press release should be evaluated together with the many uncertainties that affect Bristol-Myers Squibb's business, particularly those identified in the cautionary factors discussion in Bristol-Myers Squibb's Annual Report on Form 10-K for the year ended December 31, 2013, in our Quarterly Reports on Form 10-Q and our Current Reports on Form 8-K. Bristol-Myers Squibb undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.
Contact:
Bristol-Myers Squibb
Media:
Carrie Fernandez, 609-252-4831
cell: 215-859-2605
carrie.fernandez@bms.com
or
Investors:
Ranya Dajani, 609-252-5330
ranya.dajani@bms.com
or
Ryan Asay, 609-252-5020
ryan.asay@bms.com
All we have to do is hang in there until this treatment is approved in the United States...October maybe! Hang!!
Wednesday, June 11, 2014
Tuesday, May 20, 2014
Honey, Liver, & Sleep
The amazing benefits of Honey! With one of the side effects of Hepatitis C treatment being sleeplessness, according to this website, you can change this side effect with just 1-2 tablespoons of honey before bedtime!
Wow!! I don't know about you, but I'm going to try this remedy!
You can read all about it at: http://www.benefits-of-honey.com/honey-diet.html
Wow!! I don't know about you, but I'm going to try this remedy!
You can read all about it at: http://www.benefits-of-honey.com/honey-diet.html
Saturday, May 3, 2014
Another Baby Boomer Effected with a Bad Liver - Walter Trout
This wonderful man and musician is waiting for a liver transplant with his wife (Marie) and many fans.
Marie Trout
My cell phone rang at 6AM this morning. A quick look confirmed it was from the hospital. I felt a careful sense of optimism as I grabbed for the phone and expected to hear: “We have a liver for Walter!” But my phone froze. I couldn’t pick up the call. The phone was unresponsive. So after a few fumbling and tired attempts to answer it, I realized I had missed the call. And then the voicemail came in: “This is Doctor K.J. We are having some trouble waking Walter up; he is unresponsive, so we thought we would let you know.”
No new liver call this time. The confused and tired state of mind that Walter had been in yesterday had worsened. Now he was unconscious.
I spent the day at his bedside without making contact with him. He is deep in a place and I couldn’t reach him. Today was the first day for tears for me in a long time. Seeing him there, but without being able to sense him, was painful.
The doctors are not too worried about it. They say that this is par for the course, and the good news is that Walter is now first on the list. They assured me that the encephalopathy will reverse once a new liver goes in. They tried various other approaches to see if we could get Walter conscious – but they were unsuccessful. His vital signs remain good; he moves and has good muscle strength. His brain has not been deprived of oxygen at any point. They did a CT scan to make sure that all looked good upstairs – and it did. One very experienced and trusted doctor said that he had seen patient reverse completely after months in this state once the liver transplant took place.
Because Walter is not conscious, I decided that I don’t want to leave him here without anyone to be his advocate this weekend. Since he cannot speak for himself, I cannot leave him alone. So I called our travel agent and cancelled my flight to go see our middle son play his final show at the High School music program. That hurt too.
I called both of our sons who I am now not going to see tomorrow, and had a good talk with them. They understood. I know they were disappointed too. This disease is making it impossible to plan anything. In February I had a trip planned to go see our oldest son in Denmark and be with my mom for her birthday. Had to cancel. We had to cancel the tour I had booked for Walter and the band for 2014. The ripple effects of this disease touch so many more people than just Walter and I. Our sons, my mom, the band, our crew, fans, friends, promoters, agents, record label, publicists, you reading this right now…
I feel the pain, the disappointment, and the sorrow. There is no way of sugarcoating that. I feel for the people who are affected by this. Most of all I feel for Walter who is struggling to stay alive in a body that is polluted.
And such is life sometimes, without any easy solutions; without any quick fixes. Life can be complex, full of riddles, full of heart ache, pain and incomprehensible twists and turns. Things don’t always go the way we want.
And then just writing all of this, I also know that because things are difficult now, they won’t always be. While Walter is unresponsive right now, he won’t always be. Because I feel sad now, I won’t always be. Because our kids are disappointed now, they won’t always be. This too shall pass.
I deliberately avoid the “what if” scenarios that could be constructed by an anxious mind. I go by what the most likely outcome of all of this is going to be: A new liver for Walter. It is not in the sadness, the disappointment, and the sorrow that I would lose my fighter spirit. However, I know that if I allowed my mind to go on unsolicited trips into worry-land, I would quickly drain every last bit of hope and strength out of my being. So every time I feel my mind wanting to spin its worst-case scenarios – I stop it. I only deal with the known – and leave the unknowns to the universe.
Who knows what happens next? I continue to do all I can. And I will deal with it as it comes. I remain at Walter’s side to help him in every way I can. I tell my sons that I love them… so very much. I stay on top of business decisions as needed. I send thankful thoughts of gratitude to all of you who care to read these words. I continue my walk whether it rains, pours or shines. One step at a time! Boldly and with determination!
Walk Your Walk & Talk Your Talk...Don't give up!
Thursday, May 1, 2014
Sunday, April 27, 2014
Reversing Fatty Liver Disease
A very interesting video on Reversing Fatty Liver Disease with Dr. Sandra Cabot & Nutritionist Margaret Jasunska. They speak about the role that hormones play in telling ones brain whether you are hungry or not and about good saturated fat, insulin, and carbohydrates in people with Fatty Liver Disease. It is very important to mention that if you diet or take supplements:
Do It In Moderation! You can cause more very serious problems if you overdo any diet!
Saturday, April 12, 2014
There Is Hope - Reuters
Reuters published an article recently that shows a 98% cure rate in previously untreated Hep C patients! There is hope! It seems that all of the major drug companies are competing to come up with the best cure rate, with little side effects, for Hepatitis C. Check out the article: Merck Hepatitis C Drugs Shine in Easier to Treat Patients: Study
Wednesday, April 9, 2014
Fatty Liver Disease
Fatty Liver Disease - According to WebMD some fat in the liver is normal, but if fat makes up more than 5%-10% of the weight of your liver, you may have alcoholic or nonalcoholic liver disease. In some cases, these diseases can lead to serious complications.
Alcoholic Liver Disease (ALD) affects about 15 million American's due to the abuse of alcohol and almost all of these people develop fatty livers. This disease can occur after small or large amounts of alcohol and can be passed on through genetics or heredity.
Other factors that may influence your chances of developing alcoholic fatty liver disease include:
*Hepatitis C (which can lead to liver inflammation)
*An overload of iron
*Obesity
*Diet
*Nonalcoholic fatty liver disease (NAFLD)
Nonalcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease in the U.S. Some people with excess fat in the liver simply have what's called a fatty liver. Although this is not normal, it is not serious if it doesn't lead to inflammation or damage.
Others have what's called nonalcoholic steatohepatisis (NASH). Although it is similar to alcoholic liver disease, people with this type of fatty liver disease drink little or no alcohol. NASH can lead to permanent liver damage. The liver may enlarge and cirrhosis can occur. The liver can't work right and you may develop liver failure, liver cancer, and liver-related death. NASH is one of the leading causes of cirrhosis.
Both types of NAFLD are becoming more common. Up to 20% of adults may have either fatty liver or NASH. And more than 6 million children have one of these conditions, which are most common in Asian and Hispanic children. Recent evidence indicates that NAFLD increases the risk of heart disease in children who are overweight or obese.
Potential causes of Nonalcoholic Fatty Liver Disease (NAFLD):
The cause of NAFLD is not really clear, but it runs in families, middle aged people, overweight people, and people with high cholesterol or triglycerides, and diabetes.
Other potential causes of fatty liver disease include:
*Medications
*Viral hepatitis
*Autoimmune or inherited liver disease
*Rapid weight loss
*Malnutrition
Recent studies show that an overgrowth of bacteria in the small intestine and other changes in the intestine may be associated with nonalcoholic fatty liver disease. Some researchers now suspect this may play a role in the progression of NAFLD to NASH.
NASH or NAFLD can be treated with a good diet of low saturated fat and low fructose corn syrup. Some research says that drinking 2 cups of coffee per day can also help the disease. Other research shows that the disease is linked to low levels of Vitamin D, in those cases, a vitamin D supplement can help in the treatment of NAFLD.
Alcoholic Liver Disease (ALD) affects about 15 million American's due to the abuse of alcohol and almost all of these people develop fatty livers. This disease can occur after small or large amounts of alcohol and can be passed on through genetics or heredity.
Other factors that may influence your chances of developing alcoholic fatty liver disease include:
*Hepatitis C (which can lead to liver inflammation)
*An overload of iron
*Obesity
*Diet
*Nonalcoholic fatty liver disease (NAFLD)
Nonalcoholic fatty liver disease (NAFLD) is now the most common cause of chronic liver disease in the U.S. Some people with excess fat in the liver simply have what's called a fatty liver. Although this is not normal, it is not serious if it doesn't lead to inflammation or damage.
Others have what's called nonalcoholic steatohepatisis (NASH). Although it is similar to alcoholic liver disease, people with this type of fatty liver disease drink little or no alcohol. NASH can lead to permanent liver damage. The liver may enlarge and cirrhosis can occur. The liver can't work right and you may develop liver failure, liver cancer, and liver-related death. NASH is one of the leading causes of cirrhosis.
Both types of NAFLD are becoming more common. Up to 20% of adults may have either fatty liver or NASH. And more than 6 million children have one of these conditions, which are most common in Asian and Hispanic children. Recent evidence indicates that NAFLD increases the risk of heart disease in children who are overweight or obese.
Potential causes of Nonalcoholic Fatty Liver Disease (NAFLD):
The cause of NAFLD is not really clear, but it runs in families, middle aged people, overweight people, and people with high cholesterol or triglycerides, and diabetes.
Other potential causes of fatty liver disease include:
*Medications
*Viral hepatitis
*Autoimmune or inherited liver disease
*Rapid weight loss
*Malnutrition
Recent studies show that an overgrowth of bacteria in the small intestine and other changes in the intestine may be associated with nonalcoholic fatty liver disease. Some researchers now suspect this may play a role in the progression of NAFLD to NASH.
NASH or NAFLD can be treated with a good diet of low saturated fat and low fructose corn syrup. Some research says that drinking 2 cups of coffee per day can also help the disease. Other research shows that the disease is linked to low levels of Vitamin D, in those cases, a vitamin D supplement can help in the treatment of NAFLD.
Friday, March 14, 2014
Hep C - TV
Link: Hepatitis C News
To become a part of the Hep C News Community
Email: editor@hepatitiscnews.com
Foods to Avoid When Living with Hepatitis C
Nicole Cutler, a licensed Acupuncturist & Holistic Health Advocate talks about foods to avoid when living with Hepatitis C.
* Alcohol: Any Kind
* Fast Food: High in Fat & Calories
* High Glycemic Carbohydrates: Potatoes, Corn, White Flour, White Rice, Refined Sugar, Most Refined Breakfast Cereals
* Iron Rich Food: Eat Little to No Red Meat, Use Iron Free Vitamins, Use Iron Free Cookware, Regulating Vitamin C Intake
* Unwashed Produce: Thoroughly Wash Pesticides off of Produce
Brought to you by: Hepatitis-Central.com
Thursday, March 6, 2014
Spring is in the air!
Hello there...It has been awhile since I've posted and I have to say that I am finally feeling better. My triple treatment, for Hep C, ended in the middle of December...almost three months ago and spring is in the air! I was supposed to be finishing a 48 week treatment plan for Hep C this very weekend, but the virus broke through the treatment after five months of being virus free and treatment was stopped.
I have to say that it's been a long winter though...not only has the weather been really bad, but the cold has really effected my Cryoglobulinemia, a disease of the blood that gets worse in cold temperatures. This disease is associated, in some cases, with Hepatitis C. It has been a painful winter for me but, somehow I have become a better person.
I still may have the Hep C virus, but I have quit smoking cigarettes, drinking alcohol, and have faithfully visited my therapist once a week. I also recently cleared up a bad case of unwanted or the lack of good bacteria in my digestive system. I feel much better, my voice has gotten a lot better, and I am starting to get my strength back.
I still have another three months to go before I try another treatment for the Hep C and am really looking forward to the coming of spring, flowers, and the warm weather to be upon me and all of you!
It's amazing what a little faith can do!
Thursday, January 30, 2014
And Here I Am...
It has been several months since my doctor discontinued my treatment, virus broke through the treatment. Treatment that lasted for 9 months and of that 9 months, I was Hep C virus free for 5 months!! The first month, after treatment was discontinued, was real bad and it took me a lot of Faith and Hope to get through this month. I was sure I was going to die and if it wasn't for my therapist, my sister and brother-in-law, and another support group member, I would be back where I was a year ago...lost!!!
As it stood and still does, I have a real bad digestive problem, acid reflux problems, and a sinus infection. My liver specialist instructed me to see my primary care doctor, who is now 8 months pregnant, and at the visit I had with her last month she said she would like me to wait until some more of the drugs, from treatment, got out of my system to treat my 3 symptoms. She is now not available...and I will be seeing another physician, that does not know me!! Faith...I have to have Faith!!!
I have another 4 months until all of the Ribavirin gets out of my system. I can, at that point, start another new treatment. Sofosbuvir and Simeprevir can be taken for 12 weeks and studies have shown a 89% cure rate. You can read about this treatment at this address: New 12 week Treatment for Hep C is FDA Approved
Anyone who says that there are no post symptoms, when treatment is stopped due to virus' reappearance, is not right. I have gone from having no cryoglobulin anemia to have severe symptoms and my viral load has gone from 0 to 511,886 IU/mL in one month. I hurt all over and have developed terrible digestive problems and sinusitis.
I wish that I had a bunch of money or, should I say, enough money to try the homeopathic remedies available, at least for the next four months...I would do it. The doctor charges $450.00 as an initial fee and then you have to pay for all the medicines she prescribes. Right now I would take anything to help me feel better and hopefully this will happen soon...I have a doctors appointment next Thursday...hope my new doctor is good!!
I will check back soon and keep you updated...until then, take care of yourself!!!
As it stood and still does, I have a real bad digestive problem, acid reflux problems, and a sinus infection. My liver specialist instructed me to see my primary care doctor, who is now 8 months pregnant, and at the visit I had with her last month she said she would like me to wait until some more of the drugs, from treatment, got out of my system to treat my 3 symptoms. She is now not available...and I will be seeing another physician, that does not know me!! Faith...I have to have Faith!!!
I have another 4 months until all of the Ribavirin gets out of my system. I can, at that point, start another new treatment. Sofosbuvir and Simeprevir can be taken for 12 weeks and studies have shown a 89% cure rate. You can read about this treatment at this address: New 12 week Treatment for Hep C is FDA Approved
Anyone who says that there are no post symptoms, when treatment is stopped due to virus' reappearance, is not right. I have gone from having no cryoglobulin anemia to have severe symptoms and my viral load has gone from 0 to 511,886 IU/mL in one month. I hurt all over and have developed terrible digestive problems and sinusitis.
I wish that I had a bunch of money or, should I say, enough money to try the homeopathic remedies available, at least for the next four months...I would do it. The doctor charges $450.00 as an initial fee and then you have to pay for all the medicines she prescribes. Right now I would take anything to help me feel better and hopefully this will happen soon...I have a doctors appointment next Thursday...hope my new doctor is good!!
I will check back soon and keep you updated...until then, take care of yourself!!!
Monday, January 6, 2014
Hepatitis Slideshow Pictures: A Visual Guide to Hepatitis
I came across this wonderful slide show all about hepatitis and wanted to share it with you. Click on link: A Visual Guide to Hepatitis
Slide show is courtesy of WebMD.com!
Slide show is courtesy of WebMD.com!
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